Evaluation of Some Ecute Phase Proteins, Cytokines and Hepcidin Levels in Naturally Infected Saanen Goats with Paratuberculosis

Johne’s Disease or paratuberculosis is a mycobacterial infection of ruminants and has global economical impact. Mycobacterium avium subsp. the cause this disease. It reduces milk production, chronic weight loss leading death major losses. Acute phase reactions are defined as minimum 25% increase decrease in serum concentrations acute proteins which triggered by pro antiinflammatory cytokines released from various cells tissues. The aim study was to investigate effect subsp on blood parameters, some proteins, hepcidin naturally infected goats with paratuberculosis. In study, total 45 Saanen aged 2-5 years both sex were used animal material. Study group included 35 control 10 for evaluation. Complete counts performed taken all animals. Also interleukin 6, 10, amyloid A, haptoglobin, fibrinogen, levels evaluated samples. As result, 6 (p